Pulmonary hemorrhage in a patient with fibrillary glomerulonephritis

Article Abstract:

Fibrillary glomerulonephritis is a kidney disease characterized by deposits of fibrils -- small fibers -- in the glomerulus, the blood-filtering unit of the kidney. The fibrils usually react to antibodies to immunoglobulins, indicating that the disease may be caused by the abnormal deposition of immunoglobulins. No cases have been reported of deposition of these kinds of fibrils in other organs. A 68-year-old woman was admitted to a hospital for evaluation of chest pain and shortness of breath. She had been diagnosed with fibrillary glomerulonephritis one year prior to admission. During her hospitalization, she began coughing up blood and was subsequently diagnosed with pulmonary hemorrhage. Tissue from a lung biopsy showed fibrils similar to those found in her kidney the previous year. After several days of corticosteroid treatment, she was discharged, but re-admitted several months later with recurrent pulmonary hemorrhage. She died of respiratory failure 20 hours after admission.

Case studies, Glomerulonephritis

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Pulmonary microvascular cytology in the diagnosis of lymphangitic carcinomatosis

Article Abstract:

The diagnosis of cancer of the lymph system that has spread to the lungs is difficult to make. The authors evaluated the cellular characteristics of blood taken from patients who were later confirmed by autopsy as having lymphatic cancer. The majority of the tumors had started in the prostate, breast, esophagus and lungs. The findings were positive for patients with tumors in the lungs because of the high incidence of tumors in the major veins of the liver. The examination of cells taken from the pulmonary arteries may be useful in diagnosing lung tumors when lung biopsy, the preferable procedure, is thought to be too dangerous.

Analysis, Complications and side effects, Lungs, Cancer, Cytology, Infarction, Lymphatic metastasis, Lung biopsy

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A 54-year-old woman with acute renal failure and thrombocytopenia

Article Abstract:

A 54-year-old woman was admitted to a hospital with kidney failure and low blood levels of blood platelets, a condition called thrombocytopenia. She had a history of lupus-like symptoms. In addition to kidney failure, she developed respiratory failure and heart failure while in the hospital. This was found to be caused by widespread abnormal blood clotting, which probably caused the low platelet levels. She also tested positive for anticardiolipin antibody and the lupus anticoagulant. Both of these indicate that she had antiphospholipid-antibody syndrome. The antibodies are produced against phospholipids in cells.

Antiphospholipid syndrome

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