Pyridoxine for nausea and vomiting of pregnancy: a randomized, double-blind, placebo-controlled trial

Article Abstract:

Pyridoxine (vitamin B6) may be used to treat severe nausea during early pregnancy. Researchers compared the effect of pyridoxine to that of placebo in 336 women less than 17 weeks pregnant with severe nausea. Patients taking pyridoxine reported significantly less nausea than those taking placebo, especially in the first three days of treatment. Pyridoxine has been an ingredient in anti-nausea medications, but this study shows that it may be the only active ingredient. One drug, Debendox (Bendectin in the U.S.), included doxylamine and pyridoxine. Doxylamine has since been found to cause birth defects. This study suggests that pyridoxine by itself may safely and effectively treat severe nausea during early pregnancy.

Drug therapy, Vomiting, Pregnancy, Complications of, Pregnancy complications, Vitamin B6, Pyridoxine

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Acupressure for the in-patient treatment of nausea and vomiting in early pregnancy: A randomized control trial

Article Abstract:

A study was conducted to evaluate the efficacy of acupressure at the P6 point for the in-patient treatment of severe nausea and vomiting in early pregnancy. The result showed that the use of acupressure at the P6 point does not reduce the amount of antiemetic medication that is required, which is a requirement for intravenous fluid, and median duration of in-patient stay more than the use of placebo.

Acupressure, Morning sickness (during pregnancy), Morning sickness

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The efficacy of ginger for the prevention of postoperative nausea and vomiting: A meta-analysis

Article Abstract:

A study is carried out to specifically determine the impact of a fixed dose of ginger administration, compared with placebo, on the 24-hour postoperative nausea and vomiting. The meta-analysis of trials demonstrates that a fixed dose at least 1g of ginger is more effective than placebo for the prevention of postoperative nausea and vomiting.

Surgery, Postoperative complications, Ginger

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