Race, breast cancer subtypes, and survival in the Carolina breast cancer study

Article Abstract:

A study uses immunohistochemical (IHC) surrogates to identify breast tumor subtypes using formalin-fixed, paraffin-embedded tumor blocks collected for Carolina Breast Cancer Study (CBCS) cases, to determine associations between tumor subtypes and race, menopausal status, tumor characteristics, and survival. Basal-like breast tumors occurred at a higher prevalence among pre-menopausal African American patients compared with postmenopausal African American and non-African American patients.

Public affairs, Health aspects, Social aspects, Care and treatment, Diagnosis, Breast cancer, Postmenopausal women, Cancer survivors

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Communication of randomization in childhood leukemia trials

Article Abstract:

Many parents of children with leukemia do not understand basic aspects of medical research such as randomization, according to a study of 137 parents. Half of the parents did not understand randomization even after it was explained to them. Randomization in a clinical trial means the people participating in the trial are randomly assigned to one of two groups: the group that receives the experimental treatment and the group that does not.

Methods, Physician and patient, Physician-patient relations, Clinical trials, Childhood leukemia, Leukemia in children

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Factors associated with failure to publish large randomized trials presented at an oncology meeting

Article Abstract:

Some medical researchers who report the initial results of their study at a scientific conference may never publish the full report. Of 510 research presentations given at an annual meeting of the American Society of Clinical Oncology, 26% had not been published five years later. Studies that found a positive benefit from a treatment were more likely to be published than studies that found no benefit.

Medical publishing

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