A comparison of colonoscopy and double-contrast barium enema for surveillance after polypectomy
Article Abstract:
Colonoscopy appears to be more effective than a barium enema for detecting recurring intestinal polyps in people who have a history of these polyps. These polyps are thought to be a precursor of colorectal cancer and are removed but patients must be followed up for a recurrence. In a study of 580 patients who had a follow-up colonoscopy and a barium enema, colonoscopy detected many more polyps than the barium enema. This included polyps that were too small to be detected by a barium enema.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
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Randomized comparison of surveillance intervals after colonoscopic removal of newly diagnosed adenomatous polyps
Article Abstract:
Performing colonoscopy three years after adenomatous polyps are removed appears to be as effective in detecting colonic lesions as colonoscopy performed after both one and three years. Adenomatous polyps of the large intestine are growths that are thought to be precursors of colorectal cancer. Of 1,418 patients who had adenomatous polyps removed, 699 were scheduled to undergo medical examinations at both one year and three years, and 719 were scheduled to undergo one examination at three years. At the first examination, whether at one year or three years, there was no significant difference in the number, size and type of polyps and adenomas detected between the two groups. Altogether, adenomas were detected at follow-up in 41.7% who had two examinations and in 32% who had one examination. Given the high incidence of additional polyps at follow-up, regular surveillance is important. Delaying the first exam however, appears to be acceptable and more cost-effective.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1993
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Risk of colorectal cancer in the families of patients with adenomatous polyps
Article Abstract:
Parents and siblings of people with adenomatous polyps may have a greater risk of developing colorectal cancer than the general population. Adenomatous polyps are outgrowths of the intestine composed of noncancerous tumors which are considered precancerous. Researchers interviewed 1199 patients with adenomatous polyps and some of their siblings, parents, and children regarding a family history of cancer. Compared to spouses of patients, who were considered controls, siblings and parents of people who had polyps had 1.8 the risk of having colorectal cancer. The younger a person was found to have a polyp, the higher the risk that their siblings would have colorectal cancer. Among siblings of people with polyps, having a parent who had colorectal cancer increased the risk of colorectal cancer by approximately three times.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1996
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