Regulation of pancreatic beta-cell growth and survival by the serine/threonine kinase Akt1/PKB(alpha)
Article Abstract:
Research has been conducted on the serine/threonine kinase Akt1/PKB(alpha). The metabolic role of AKT in a mammalian model has been investigated via the creation of a transgenic mouse with the active form of Akt1 expressed in the pancreatic beta cells.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
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Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease
Article Abstract:
This article discusses how mice affected with neurodegenerative metabolic disease are used to show how intra-cranial transplantation of neural stem cells delayed the disease. A detailed explanation is provided which shows that stem cells possess properties that prolong the survival of the disease-infected mouse.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
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B lymphocyte-directed immunotherapy promotes long-term islet allograft survival in nonhuman primates
Article Abstract:
The importance of the B lymphocyte-directed immunotherapy in promoting long-term islet allograft survival in nonhuman primates is discussed. It is observed that B lymphocytes highly increase the chances of the primates' achievement of humoral transplantation tolerance.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
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