Rethinking electronic health records to better achieve quality and safety goals
Article Abstract:
Introduction of information technology needs to be approached as an iterative process of care improvement instead of a one-time insertion of an information system into established practice. Information technology supports a family of technological methodologies, each with unique mechanisms of action, benefits and side effects, thus a staged method to turning direct access by patients to their health information into more effective care is presented.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2007
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The drug development crisis: Efficiency and safety
Article Abstract:
Technologic methods for improving drug development efficiency are analyzed, which comprises high-content cell screening, expression profiling, mass spectroscopy, mouse models of disease, and post-launch screening program that allows investigation of adverse drug effects. Findings reveal that implementation of these new technologies assures improved performance in drug development and safety.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2007
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Idiosyncratic toxicity: A convergence of risk factors
Article Abstract:
Studies reveal that idiosyncratic toxicities are normally not observed until a drug has been on the market and has gained broad exposure. It is observed that idiosyncratic toxicity can happen when a convergence of risk factors, including drug exposure, tips the risk-benefit balance away from benefit and toward risk.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2007
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