Risk factors and clinical presentation of acute primary HIV infection in India
Article Abstract:
Testing blood samples for the HIV p24 antigen may help detect HIV infection earlier. This viral protein is produced when the virus is actively reproducing and may occur sooner than the antibodies that most HIV tests rely on. Researchers tested blood samples from 3,874 people who tested negative for HIV antibodies for the p24 antigen. Fifty-eight tested positive. Unprotected sex with prostitutes and genital ulcers were risk factors for HIV infection. Fever, joint pain and night sweats were more common in p24-positive persons, occurring in almost half. These could be signs of early HIV infection.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
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Spread of HIV infection in married monogamous women in India
Article Abstract:
HIV-infected men in India may be spreading the virus to their uninfected wives. Researchers tested 916 Indian women attending sexually transmitted disease clinics for HIV, 525 of whom were prostitutes. Half of the prostitutes and 14% of the remaining women were infected. Prostitutes who had genital ulcers or did not use condoms consistently were more likely to become infected. In the remaining women, sexual intercourse with a man with a sexually transmitted disease was the biggest risk factor. Since many of these women were monogamous, it seems likely that their husbands infected them.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
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Acute primary HIV infection
Article Abstract:
Acute primary HIV infection must be diagnosed as soon as possible so that aggressive treatment can begin. When someone is infected with HIV, they often develop flu-like symptoms 2 to 6 weeks later. The symptoms last about 1-2 weeks and then the person often becomes asymptomatic. It is during the initial stages of infection that they are most infectious and early treatment has been shown to reduce the virus to undetectable levels. The best diagnostic test is measuring blood levels of p24 antigen or viral RNA, which are present even in the absence of antibodies.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
User Contributions:
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