Risk for HIV-1 infection associated with a common CXCL 12 (SDF1) polymorphism and CXCR4 variation in an African population
Article Abstract:
A study was conducted on African people to analyze the stromal cell derived factor 1 (SDF1)-3'A single nucleotide polymorphism (SNP) and performed mutation screening for polymorphic markers in the chemokine receptor 4 (CXCR4) gene to determine existence of significant associations with susceptibility to HIV-1 infection. Comprehensive mutation analysis of the CXCR4 gene confirmed a high degree of genetic conservation within the coding region of African ancient populations.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
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Polymorphism of the L1 capsid gene and persistence of human papillomavirus type 52 infection in women at high risk or infected by HIV
Article Abstract:
The polymorphism of L1 capsid gene and its association with human papillomavirus 52 (HPV-52) persistence in women at risk or infected by HIV are evaluated. The results have shown that L1 variations are unlikely to predispose to HPV-52 persistence and hence do not help in identifying women at greater risk for high-grade squamous intraepithelial lesions (HSILs).
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2007
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Genotyping of pneumocystis jiroveci pneumonia in Italian AIDS patients
Article Abstract:
The investigation carried out to determine possible relation between internal transcribed spacer (ITS) genotypes and dihydropteroate synthase (DHPS) mutations showed no correlation between Pneumocystis jiroveci ITS types and specific clinical characteristics.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2007
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