Safety, Immunogenicity, and Induction of Immunologic Memory by a Serogroup C Meningococcal Conjugate Vaccine in Infants: A Randomized Controlled Trial
Article Abstract:
A meningococcal C conjugate vaccine can protect babies from developing meningitis caused by Neisseria meningitidis. This bacterium is a common cause of meningitis in babies all over the world. In a study of 182 babies, one dose of the conjgate vaccine at 2, 3, and 4 months resulted in antibodies against the bacterium that persisted up to one year of age. The vaccine was well-tolerated and can be given with other vaccines.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
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Antibody Concentration and Clinical Protection After Hib Conjugate Vaccination in the United Kingdom
Article Abstract:
It may not be necessary to give two-year-old children a booster shot of Hib vaccine if they received the first three doses as babies. In a study of 260 children who only received the first three doses, levels of protective antibodies decreased over time, but remained high enough until six years of age.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
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Immunogenicity and safety of a combination pneumococcal-meningococcal vaccine in infants: A randomized controlled trial
Article Abstract:
The safety and immunogenicity of a combination 9-valent pneumococcal-group C meningococcal conjugate candidate vaccine (Pnc9-MenC) administration as part of the routine UK infant immunization schedule at ages 2,3, and 4 months is determined. Results revealed that Pnc9-MenC combination vaccine administered to infants at ages 2,3, and 4 months demonstrated reduced group C meningococcal immunogenecity compared with MenC vaccine.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
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