Screening for Chlamydia - a key to the prevention of pelvic inflammatory disease

Article Abstract:

A nationwide prevention program to screen women at risk for chlamydial infection could significantly reduce the incidence of pelvic inflammatory disease. Pelvic inflammatory disease can occur when the bacterium moves up the genital tract. It can result in scarring of the uterus and Fallopian tubes, which increases the risk of infertility and ectopic pregnancy. But many women with pelvic inflammatory disease have no symptoms or delay seeing a doctor. And many are not compliant with the treatment. So the best treatment is to prevent pelvic inflammatory disease by promptly identifying and treating women with chlamydial infections. A 1996 study found that testing women at high risk for chlamydial infections and treating those who tested positive reduced the incidence of pelvic inflammatory disease by 56%. Similar results have occurred in Sweden over the past 20 years. Accurate DNA tests and single-dose treatments could significantly reduce the complications of chlamydial infections.

Editorial, Prevention, Pelvic inflammatory disease

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Reduction of false negative results in screening of newborns for homocystinuria

Article Abstract:

A cutoff level of 1milligram (mg) of methionine per deciliter of blood appears to be more effective in identifying newborn babies who have homocystinuria. This metabolic disorder is caused by an enzyme deficiency that causes elevated blood levels of homocysteine and methionine. If the disease is diagnosed early, it can be treated, sparing the baby from severe brain damage. In 1990, the cutoff level for screening newborn babies was lowered from 2 mg per deciliter to 1 mg per deciliter. Of the seven babies identified since then, five had methionine levels below 2 mg per deciliter and would not have been detected using the old cutoff level.

Statistical Data Included, Medical examination, Infants (Newborn), Neonatal screening, Homocystinuria

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Genital chlamydial infections

Article Abstract:

A summary of the evidence for and against screening certain people for chlamydia infection is presented. Topics include clinical presentation, epidemiology, screening women, screening men, testing methods, common clinical syndromes and their treatment, infection during pregnancy, and pelvic inflammatory disease. Screening guidelines from seven different organizations and associations are also included.

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