Screening for cystic fibrosis - time to change our position?

Article Abstract:

It may be time to screen all newborn babies for cystic fibrosis. The prognosis of cystic fibrosis has improved and diagnosing affected children early could improve their lives even more. A 1997 study found that infants diagnosed with cystic fibrosis very soon after birth were longer and heavier than those diagnosed later. Early diagnosis could thus prevent nutritional disorders in these children. It may also preserve lung function for longer periods. Testing has become more accurate and early diagnosis may spare the parents from much anxiety. It will also help them plan future pregnancies.

Health aspects, Editorial, Diagnosis, Testing, Infants (Newborn), Newborn infants, Medical screening, Health screening

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Use of lasers for vision correction of nearsightedness and farsightedness

Article Abstract:

The vast majority of patients who undergo photrefractive keratectomy (PRK) or laser-assisted in situ keratomileusis (LASIK) have an improvement in uncorrected visual acuity, in the hands of an experienced and competent surgeon. PRK, LASIK, and laser-assisted subepithlial keratomileusis (LASEK) are relatively effective and predictable surgical procedures for the correction of nearsightedness and farsightedness with or without low-to moderate astigmatism.

All Other Miscellaneous Electrical Equipment and Component Manufacturing, Lasers, Lasers & Related Equip, Care and treatment, Usage, Vision disorders, Laser

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Gentamicin-induced correction of CFTR function in patients with cystic fibrosis and CFTR stop mutations

Article Abstract:

The antibiotic gentamicin can correct one of the gene defects that causes cystic fibrosis, according to a study of 25 patients who had a stop mutation in the CFTR gene. The drug was applied to their nasal mucosa and it restored the normal function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein in 90% of the patients. In 68% of the patients, chloride or sodium transport in the nose was restored to normal.

Evaluation, Drug therapy, Gentamicin, Gentamicins

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