Serum squamous cell carcinoma antigen levels in invasive cervical cancer: prediction of response and recurrence

Article Abstract:

The rate of normalization of elevated serum squamous cell carcinoma (SCC) antigen levels in patients with cervical cancer does not appear to be associated with the outcome. Previous studies have found that SCC levels are associated with the extent of the disease and serve as an indicator of prognosis and disease recurrence. Among 107 patients with squamous cell cancer of the cervix, elevated SCC antigen levels increased with the severity of disease. Elevated SCC antigen levels were detected in 24% of the patients with stage I cancer, 57% with stage II, 67% with stage III and 71% with stage IV. Elevated SCC levels were also detected in 50% of the women with recurrent disease. Normalization of SCC antigen levels after therapy most accurately predicted the patient's response. Neither the initial level of SCC antigen nor the rate of normalization predicted therapeutic response.

Measurement, Prognosis, Tumor markers, Squamous cell carcinoma antigen

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Exacerbation of endometriosis as a result of premenopausal tamoxifen exposure

Article Abstract:

Doctors describe the case of a 41-year-old woman whose endometriosis got worse when she began taking tamoxifen for breast cancer. She eventually developed a mass in her abdomen that had to be surgically removed. Endometriosis occurs when blood from the uterus occurs outside of the uterus.

Causes of, Complications and side effects, Drug therapy, Breast cancer, Endometriosis, Tamoxifen

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Radical abdominal trachelectomy and pelvic lymphadenectomy with uterine conservation and subsequent pregnancy in the treatment of early invasive cervical cancer

Article Abstract:

Women with cervical cancer who were treated surgically with a radical trachelectomy may still be able to have a successful pregnancy. In a study of three patients who had this operation, all began menstruating normally and one had a successful pregnancy delivered by cesarean.

Health aspects, Surgery, Cancer patients

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