Successful antepartum treatment of listeriosis

Article Abstract:

The case report is presented of a 26-year-old woman, 27 weeks' pregnant with her first child, who became ill with a flu-like illness with fever, backache, and muscle pain. A blood-tinged vaginal discharge began one week later, and uterine contractions were detected. The patient was given a drug to inhibit contractions (a tocolytic drug), and blood, cervical, and uterine cultures were taken. The blood cultures indicated the presence of Listeria monocytogenes, the organism that causes listeriosis, a serious infection that can be transmitted to the fetus. Antibiotics were administered, with the tocolytic drug, and the symptoms continued. However, fetal activity, which had become undetectable by the mother, became normal again. Labor began three days later, and a boy was born by cesarean section. He had signs of intrauterine infection and was treated with antibiotics; a ventilator was necessary for several days, and the infant was discharged home in excellent condition at the age of 50 days. The placenta was found to be no longer functional and contained abscesses and other signs of acute infection. Pregnant patients who develop an illness similar to influenza, especially in the last three months of pregnancy, should be tested for listeria infections, which are most accurately diagnosed by blood test. Untreated, the disease is often fatal to the fetus, or associated with serious complications; antibiotic treatment, usually with intravenous ampicillin, is effective. A source of Listeria monocytogenes can be cheese made from unpasteurized milk. In the case presented, antibiotic therapy was administered while tocolytic treatment delayed premature birth for several days. (Consumer Summary produced by Reliance Medical Information, Inc.)

Case studies, Infection, Diagnosis, Fetus, Pregnant women, Listeriosis

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Preliminary results of 5% immiquimod cream in the primary treatment of vulva intraepithelial neoplasia grade 2/3

Article Abstract:

A study on the tolerability and efficacy of 5% imiquimod cream in the primary treatment of vulva intraepithelial neoplasia (VIN) grade 2/3 was conducted. The results revealed that the imiquimod cream could induce histologic regression of high-grade VIN lesions and were well tolerated using a slow dosw-esclating regime.

Vulva

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Reversible peripartum liver failure: a new perspective on the diagnosis, treatment, and cause of acute fatty liver of pregnancy, based on 28 consecutive cases

Article Abstract:

Pregnant women who develop acute fatty liver of pregnancy can be managed on the basis of symptoms and will have an excellent prognosis. Acute fatty liver of pregnancy is a rare disorder characterized by the accumulation of fat in the liver. It usually occurs during the third trimester.

Prognosis, Fatty liver

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