Mycophenolate mofetil - a new immunosuppressant for organ transplantation
Article Abstract:
Mycophenolate mofetil (CellCept) may be more effective and only slightly more toxic than azatioprine in preventing kidney rejection in patients after transplantation. Mycophenolate mofetil should be taken with cyclosporine and corticosteroids. A better initial benefit was seen in patients receiving 2 or 3 grams (g) of mycophenolate mofetil compared to patients who took azathioprine. After six months, however, there was no difference between groups with respect to survival. Mycophenolate mofetil apparently prevents organ rejection better than placebo and may be effective in patients who have had previous graft rejections. Drug side effects include diarrhea and reduction in white blood cells, and are slightly worse than those associated with azathioprine, especially at higher doses. The cost of mycophenolate mofetil is more than four times higher than that of azathioprine.
Publication Name: Medical Letter on Drugs and Therapeutics
Subject: Health
ISSN: 0025-732X
Year: 1995
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Effect of hydrostatic confining pressure on the failure mode and compressive strength of polycrystalline ice
Article Abstract:
The effect of hydrostatic confining pressure on the compressive strength and failure mode of polycrystalline ice was investigated. Compressive tests were carried out on fine and coarse-grained granular ice with grain size of one and 10 mm and coarse-grained columnar ice at various strain rates under hydrostatic confining pressure. Experimental results showed that the compressive fracture/yield stress increased as confining pressure increased up to a critical level at which the stress reached a maximum and the process of failure changed from brittle to ductile.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 1998
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Swazi safari
Article Abstract:
Family nurse practitioners are providing primary health care in Swaziland due to a shortage of doctors. A one year training course prepares experienced nurses to run Swaziland's 134 rural clinics. Nurses are trained to deal with physical and psychological health problems. Community health and preventive medicine is emphasised. Family planning and child health are encouraged. After training the FNP will be able to examine, diagnose, prescribe or refer patients suffering most primary health care problems.
Publication Name: Nursing Times
Subject: Health
ISSN: 0954-7762
Year: 1992
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