The Origins of Alzheimer Disease: A Is for Amyloid
Article Abstract:
Research on the amyloid protein may lead to early diagnostic tests and effective treatments to prevent Alzheimer's disease. Amyloid protein is a normal protein in the brain, but some gene mutations cause an abnormal form of the protein that accumulates in the brain. A study published in 2000 found that the accumulation of this abnormal protein could be found in brain autopsy samples in patients with do significant dementia. If a blood test for this protein could be developed, Alzheimer's disease could be diagnosed in the very early stages. Drugs might be designed that could block the accumulation of the abnormal protein without affecting the normal form.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
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Intercontinental Epidemiology of Alzheimer Disease: A Global Approach to Bad Gene Hunting
Article Abstract:
A study comparing the rate of dementia and Alzheimer's disease in African-Americans and Nigerians shows that genetic, environmental, and even dietary factors may be involved. The study found that the rate of dementia and Alzheimer's disease was two to three times higher in African-Americans than in Nigerians.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
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Age-related testosterone depletion and the development of Alzheimer disease
Article Abstract:
Research suggests that low brain testosterone may hinder beneficial neural affects of androgens and therefore may be a risk factor for Alzheimer's disease in men.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
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