The Preterm Prediction Study: toward a multiple-marker test for spontaneous preterm birth

Article Abstract:

Cervical length, fetal fibronectin, maternal alpha fetoprotein, alkaline phosphatase, and granulocyte colony-stimulating factor can predict which pregnant women will deliver prematurely, according to a study of 2,929 women. Premature babies have a high rate of death and future disability.

Diagnosis

---

The preterm prediction study: risk factors in twin gestations

Article Abstract:

An abnormally short cervix and the presence of fetal fibronectin in cervical fluid appear to predict premature birth in twin pregnancies. Researchers screened 147 women with twin pregnancies for more than 50 risk factors for premature delivery as well as culturing them for vaginal bacteria and measuring cervical length and testing for fetal fibronectin periodically between 24 and 30 weeks gestation. Short cervical length at 24 weeks had the strongest association with premature delivery. Fetal fibronectin at 28 weeks predicted premature delivery before 32 weeks.

Physiological aspects, Pregnancy, Multiple, Multiple pregnancy

---

The Preterm Prediction Study: recurrence risk of spontaneous preterm birth

Article Abstract:

Women with a history of premature birth are likely to deliver prematurely in subsequent pregnancies if they test positive for fetal fibronectin and have short uterine cervixes. Researchers tested vaginal and cervical fluid samples from 1,282 pregnant women for fetal fibronectin at 24 weeks' gestation and used ultrasound to measure their cervixes. Women who tested negative for fetal fibronection and had long cervixes had the lowest rate of premature birth (7%) whereas women who tested positive for fetal fibronectin and had short cervixes had the highest rate (64%). A positive fetal fibronectin test increased the risk even in women with long cervixes.

Similar abstracts:

• Abstracts: The Preterm Prediction Study: can low-risk women destined for spontaneous preterm birth be identified? Occupational fatigue and preterm premature rupture of membranes
• Abstracts: The Preterm Prediction Study: failure of midtrimester cervical sialidase level elevation to predict subsequent spontaneous preterm birth
• Abstracts: The Alabama preterm birth project: Placental histology in recurrent spontaneous and indicated preterm birth. Midtrimester vaginal Mycoplasma genitalium in women with subsequent spontaneous preterm birth
• Abstracts: Two-stage elevation of cell-free fetal DNA in maternal sera before onset of preeclampsia. Effects of Vitamin E on Lipid Peroxidation in Healthy Persons
• Abstracts: Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.