The challenge of minority recruitment in clinical trials for AIDS
Article Abstract:
In 1989, almost half of all reported AIDS cases were African-Americans and Hispanics, but minorities are underrepresented in clinical trials that evaluate new treatments for AIDS. Minorities with AIDS may distrust or not understand medical research and dislike the idea of being a 'guinea pig'. They are often poor, and can not afford to travel to the site of a clinical trial, which is often a large university or medical center. They often get their medical care in a hospital emergency room, and may not have a private physician to refer them to a trial. The experience of gay men with AIDS has shown that groups can influence how medical research is done. But in the case of minorities, research trials must include funding for transporting patients, feeding them, providing child care and counseling them about drug use. The Harlem AIDS Treatment Group is a model for such trials.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1992
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Effect of the statistical significance of results on the time to completion and publication of randomized efficacy trials
Article Abstract:
Clinical trials that demonstrate a statistically significant benefit from treatment may be published sooner than those with negative results. Researchers reviewed 101 AIDS research trials to determine the total time from the start of research to the publication of results in medical journals. Trials with positive results reached publication in an average of 4.3 years, compared to 6.5 years for trials that showed little or no benefit of the tested treatment. Delays in submission and publication of research may result in a bias that favors studies with positive outcomes.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
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Mentoring program supports new generation of HIV researchers
Article Abstract:
HIV researchers in San Francisco have taken steps to empower the next generation of scientists to join the war against the potentially deadly infection, as the aids epidemic reaches the midpoint of its third decade in 2006. They have launched an ambitious mentoring initiative, targeted at developing and encouraging young researchers committed to a career in HIV research.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
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