The prevention of heart failure - a new agenda
Article Abstract:
Three different research studies evaluated the use of angiotensin-converting-enzyme (ACE) inhibitors to prevent heart failure in patients with cardiac dysfunction. Patients who have had a heart attack often have damage to their heart that causes progressive cardiac dysfunction. One study found that treatment with enalapril before the onset of heart failure did not increase survival significantly in patients with left ventricular dysfunction. In patients with left ventricular dysfunction, the heart is incapable of pumping enough blood to the rest of the body. Treatment with enalapril did increase survival by 8%, which may hold some promise for the future. Another study found that early treatment with captopril in heart attack patients with some left ventricular dysfunction may increase survival. The third study found that starting early treatment of heart attack patients with enalapril did not increase survival.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1992
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Prevention of end-stage renal disease due to type 2 diabetes
Article Abstract:
ACE inhibitors and angiotensin II-receptor blockers appear to slow the progression of kidney disease in people with type 2 diabetes and should be used more often. The number of people with type 2 diabetes is increasing, and diabetes is a major risk factor for end-stage kidney disease.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
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