A study of human leukocyte antigen G expression in hydatidiform moles

Article Abstract:

Human leukocyte antigen (HLA) G is expressed in hydatidiform moles, indicating that HLA G may protect the fetus from rejection by the mother's immune system. Hydatidiform moles are a collection of embryonic cells that never develops into a fetus.

Physiological aspects, HLA histocompatibility antigens, HLA antigens, Molar pregnancy, Hydatidiform mole

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Decidual NK cells regulate key developmental processes at the human fetal-maternal interface

Article Abstract:

Studies demonstrate that decidual NK (dNK) cells regulate trophoblast invasion and that these cells are potent secretors of angiogenic factors inducing vascular growth in the decidua. Such functions are regulated by specific interactions between dNK-activating and dNK-inhibitory receptors and their ligands, uniquely expressed at the fetal-maternal interface and the overall results support reproductive immunology and reproductive tissue development.

United States, Science & research, Maternal-fetal exchange, Developmental biology, Cellular control mechanisms, Cell regulation, Trophoblast, Trophoblasts

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The role of midtrimester targeted fetal organ screening combined with the "triple test" and maternal age in the diagnosis of trisomy 21: a retrospective study

Article Abstract:

Using ultrasound to measure anatomic abnormalities associated with fetal chromosome abnormalities may be useful when combined with other diagnostic tests. Researchers combined ultrasound measurements with maternal age and a series of biochemical measurements to detect trisomy 21 in 67,092 pregnancies. Trisomy 21 occurs when the baby has three copies of chromosome 21. Ninety-two percent of the trisomy 21 cases were detected when this technique was performed.

Methods, Diagnosis, Fetus, Medical screening, Health screening, Down syndrome

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