Three-phase study of phlebitis in patients receiving peripheral intravenous hyperalimentation
Article Abstract:
Administration of intravenous fluid may be complicated by the development of phlebitis, an inflammation of the vein. This is especially true of patients receiving intravenous hyperalimentation (extra nutrition). There are many possible sources of infection. A three-part study was undertaken at one hospital to determine the sources of phlebitis and methods of prevention. Phlebitis occurred in 57 of 88 patients (65 percent) receiving hyperalimentation through a peripheral vein. The incidence of phlebitis occurring in patients receiving intravenous therapy other than hyperalimentation was 84 of 456 patients (18 percent). A study of 50 patients scheduled to receive hyperalimentation was undertaken to determine if bacteria or particulate matter was the cause of the phlebitis. The results indicated that neither filtration of particles nor bacteria was able to be implicated in the development of phlebitis. When the base of infused hyperalimentation solution was changed from the standard glucose-based to a glycerol-based, the incidence of phlebitis decreased from 68 to 27 percent. It is concluded the phlebitis in hyperalimentation patients is probably the result of the chemical properties of the solution itself rather than bacteria or particulate matter. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: American Journal of Surgery
Subject: Health
ISSN: 0002-9610
Year: 1990
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Aspirin for cancer
Article Abstract:
Non-steroidal anti-inflammatory drugs appear to inhibit angiogenesis, which is the formation of new blood vessels. This can explain how NSAIDs could protect against cancer but cause gastrointestinal ulcers, since carcinogenesis and wound healing both depend on angiogenesis.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
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Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing
Article Abstract:
Non-steroidal anti-inflammatory drugs inhibit angiogenesis, which would explain how they can prevent certain types of cancer and also cause gastric ulcers. Angiogenesis is involved in tumor growth and wound healing.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
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