Mortality over a period of 10 years in patients with peripheral arterial disease

Article Abstract:

Individuals with arteriosclerosis in the large veins of the legs (large-vessel peripheral arterial disease) may have an increased risk of dying from cardiovascular diseases, including coronary artery disease. Of 475 individuals examined for the presence of large-vessel peripheral arterial disease, 67 were diagnosed with the disease. After 10 years, 61.8% of the men and 33.3% of the women with large-vessel peripheral arterial disease had died, compared with 16.9% of the men and 11.6% of the women without the disease. After adjusting for other risk factors for cardiovascular disease, individuals with large-vessel peripheral arterial disease were three times more likely to die from any cause, six times more likely to die from cardiovascular diseases and almost seven times more likely to die from coronary artery disease than individuals without the disease.

Arterial occlusions, Arterial occlusive diseases, Intermittent claudication

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Kashin-Beck osteoarthropathy in rural Tibet in relation to selenium and iodine status

Article Abstract:

Iodine deficiency appears to be the cause of Kashin-Beck osteoarthopathy in rural Tibet rather than selenium deficiency. Kashin-Beck osteoarthopathy is a degenerative joint disease seen in many areas of Tibet. Researchers measured thyroid function and blood selenium levels in 575 Tibetans from 12 villages around Lhasa, Tibet. None of the residents of one village had Kashin-Beck osteoarthopathy. Half of the 575 Tibetans had Kashin-Beck osteoarthopathy and half also had goiter, which is a sign of iodine deficiency. Many also had selenium deficiency, but only iodine deficiency was linked to Kashin-Beck osteoarthopathy.

Risk factors, Diseases, Osteoarthritis, Iodine deficiency diseases, Tibetans

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Mortality after the treatment of hyperthyroidism with radioactive iodine

Article Abstract:

Hyperthyroidism appears to have a substantial impact on mortality, especially from cardiovascular disease. Hyperthyroidism is characterized by excessive production of thyroid hormones. Researchers studied mortality rates among 7,209 people who had received radioactive iodine to treat hyperthyroidism between 1950 and 1989. The death rate was higher in these patients than would be expected in the general population. The risk of death from thyroid disease was 25 times higher than normal and the risk of death from cardiovascular disease and hip fractures was also elevated.

Cerebrovascular disease, Cerebrovascular disorders, Thyroid diseases, Hyperthyroidism

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