What we learn from infants with brain tumors
Article Abstract:
Radiation therapy to treat brain tumors in infants and young children is effective but causes intellectual dysfunction, growth retardation and hormone deficiency. A 1993 study showed that chemotherapy can delay these children's need for radiation therapy. However, most of the children still died of the disease. New developments in supportive therapy for cancer patients receiving chemotherapy could improve survival rates. These supportive measures include giving patients granulocyte colony-stimulating factor and bone marrow transplants to boost the immune system. It is not clear if there is any safe age to give radiation treatment, nor if chemotherapy will damage a child's brain.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1993
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Pallidal deep-brain stimulation in primary generalized or segmental dystonia
Article Abstract:
The clinical efficacy and safety of bilateral pallidal deep-brain stimulation for severe primary dystonia in a series of 40 patients who participated in a prospective trial of neurostimulation is reported. In this randomized comparison of the effects of neurostimulation and sham stimulation it was found that bilateral high-frequency stimulation of the internal globus pallidus is efficacious in the reduction of movement impairment and disability in patients with primary generalized or segmental dystonia.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
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