Santiago Ramon y Cajal and methods in neurohistology
Article Abstract:
Spanish neurohistologist Santiago Ramon y Cajal was an innovative scientist and a true artist. In his studies of the nervous system, he used a modified Golgi technique to achieve adequate impregnation and better resolution. Ramon y Cajal drew and described these stained specimens faithfully which were then published in different languages. Ramon y Cajal also used modern instruments of his era, which included the technical camera lucida and continually upgraded Zeiss microscopes and cameras. His works are a valuable contribution to neuroscience and his efforts truly deserve his 1906 Noble Prize and other awards.
Publication Name: Trends in Neurosciences
Subject: Psychology and mental health
ISSN: 0166-2236
Year: 1992
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Three-dimensional images of Ramon y Cajal's original preparations, as viewed by confocal microscopy
Article Abstract:
Three-dimensional images of the impregnated neurological specimens of neurohistologist Santiago Ramon y Cajal are viewed through confocal microscopy. Confocal microscopes produce images of narrow focal planes whose depth can be increased using optical, mechanical or image-summing devices. The different colors of the specimens as projected by the precipitates were balanced using a tungsten filament source instead of a mercury lamp. The angle of view was also taken into account in the photography of the impregnated specimens, which resulted in precise and brightly colored pseudoholograms.
Publication Name: Trends in Neurosciences
Subject: Psychology and mental health
ISSN: 0166-2236
Year: 1992
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T.P.S. Powell (1923-1996)
Article Abstract:
Tom Powell was one of the scientists who pioneered researches in modern neuroscience. His works resulted from the influences of Le Gros Clark with whom he worked during his early years as a neuroanatomist. He conducted researches on the spread of Alzheimer cells in the human brain and his background on the retrograde degeneration method and on the olfactory system aided in his understanding of the disease. Powell's researches served as basis for subsequent scientific endeavors by other neuroscientists. His students in neuroanatomy regarded him as a brilliant teacher.
Publication Name: Trends in Neurosciences
Subject: Psychology and mental health
ISSN: 0166-2236
Year: 1996
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