Single-molecule RNA folding
Article Abstract:
A review of the developments in the field of RNA folding that are made possible by single-molecule experiments, focusing on those using fluorescence resonance energy transfer (FRET) is presented. The results suggested that stable secondary structures are partly responsible for the rugged energy landscape of RNA, a complete mechanistic understanding of the complex folding behavior is not obtained.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
Probing single-molecule protein conformational dynamics
Article Abstract:
Protein conformational fluctuations and dynamics, often complex and associated with inhomogeneities that play a crucial role in biomolecule functions cannot be easily characterized. Single-molecule spectroscopy is powerful for identifying and characterizing spatially and temporally inhomogeneous protein conformational dynamics.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
Solvation dynamics and proton transfer in supramolecular assemblies
Article Abstract:
Research shows that water molecules are in a confined state in supramolecular assemblies and exhibit an ultraslow component of solvation that is slower than that in bulk water by 2-4 orders of magnitude. Data indicate that this is due to the disruption of hydrogen-bond network of water and water binding to macromolecules.
Publication Name: Accounts of Chemical Research
Subject: Science and technology
ISSN: 0001-4842
Year: 2003
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Policies for science and technology. Pan-American science collaboration. President Clinton's science advisor
- Abstracts: Lattices may put security codes on a firmer footing. Error-correcting code keeps quantum computers on track. If you're stumped, try something harder: mathematics
- Abstracts: Stochastic aspects of matrix cracking in brittle matrix composites. Finite element simulations of fiber pull-out
- Abstracts: Applicability of Neuber's rule to the analysis of stress and strain concentration under creep conditions. Compressive failure of fiber composites: the roles of multiaxial loading and creep
- Abstracts: New images wet researchers' appetites. Closing in on superconductivity