A novel intron site in the triosephosphate isomerase gene from the mosquito Culex tarsalis
Article Abstract:
An intron in a gene from the mosquito Culex tarsalis supports the exon- shuffling hypothesis and the idea that introns came early in evolution. The gene site is for triosephosphate isomerase, and the intron splits an exon that would have made modules for two proteins. The exon-shuffling hypothesis predicts such an intron position for the purpose of protein formation, and this would imply that introns arose at the same time as genes instead of later in evolution.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
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Genes-in-pieces revisited
Article Abstract:
An intron in a gene of the mosquito Culex tarsalis supports the exon-shuffling hypothesis and the idea that introns came early in evolution. Claus Tittiger and colleagues found a unique intron site in the gene for triosephosphate isomerase. The intron splits an exon which would have made modules for two proteins, as the exon-shuffling hypothesis predicts. More research is needed to confirm the idea that introns came early instead of later in genetic evolution.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
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Why introns-in-pieces?
Article Abstract:
New evidence for the presence of self-splicing group II introns deep inside bacteria supports Cavalier-Smith's 1991 'introns-late' theory. Scientists had thought such introns existed only in chloroplast and mitochondrial genomes, but Jean-Luc Ferat and Francais Michel have found them in those organelles' bacterial antecedents. This implies revisions in theories of how introns evolve, and may prove troublesome to the 'introns-early' theory.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
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