Absence of S6K1 protects against age-and diet-induced obesity while enhancing insulin sensitivity

Article Abstract:

A report that S6K1-deficient mice are protected against obesity owing to enhanced beta-oxidation is presented. In case of fat diet, levels of glucose and free fatty acids still rise in S6Ki-deficient mice resulting in insulin receptor desensitization.

United States, Science & research, Health aspects, Obesity, Ribosomal proteins

---

The lipid phosphatase SHIP2 controls insulin sensitivity

Article Abstract:

Research into mice lacking type-II SH2-domain-containing inositol 5-phosphatase, or SHIP2, shows that its loss causes increased sensitivity to insulin.

Physiological aspects, Phosphatases

---

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice

Article Abstract:

Mice deficient for S6 kinase 1 are found to by hypoinsulinaemic and glucose intolerant.

Similar abstracts:

• Abstracts: Control of protein-ligand recognition using a stimuli-responsive polymer. Size-dependent control of the binding of biotinylated proteins to streptavidin using a polymer shield
• Abstracts: Universities protest against Australian spending cuts. Cuts spark strike at Australian universities. Clean-up strategy at Australian nuclear site called into question
• Abstracts: The superficial life of microbes. DNA protection by stress-induced biocrystallization. A role for excreted quinones in extracellular electron transfer
• Abstracts: Penguins disturbed by tourists. Energy saving in flight formation. Oceanic respite for wandering albatrosses
• Abstracts: Activation of the primary visual cortex by Braille reading in blind subjects. The relative metabolic demand of inhibition and excitation

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.