Allosteric modulation of the presynaptic Ca(super 2+) sensor for vesicle fusion
Article Abstract:
An investigation on whether the potentiation of neuro-transmitter release by phorbol esters, which target presynaptic protein kinase C (PKC)/munc-13 signalling cascades, exerts a direct effect on the Ca(super 2+) -sensitivity of vesicle fusion is presented. The results revealed that phorbol esters potentiate transmitter release by increasing the apparent Ca(super 2+) -sensitivity of vesicle fusion.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Direct modulation of synaptic vesicle priming by GABA (sub)B receptor activation at a glutamatergic synapse
Article Abstract:
The authors descuss the study of second messenger cascade involving G proteins. They demonstrate that G-protein-mediated signalling, including gamma-amino butyric acid subtype B receptors, causes synaptic vesicle recruitment retardation during the sustained activity and after the short-term depression.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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Intracellular calcium dependence of transmitter release rates at a fast central synapse
Article Abstract:
Research is presented concerning the influence of neurotransmitter release and calcium-triggered fusion of synaptic vessels in the central nervous system's signalling ability.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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