An essential role of CoREST in nucleosomal histone 3 lysine 4 demethylation
Article Abstract:
BHC110-containing complexes reveal a nearly fivefold increase in demethylation of histone H3 lysine 4 (H3K4) compared to recombinant BHC110. In vitro reconstitution of the BHC complex using recombinant subunits reveals an essential role for the REST corepressor CoREST in stimulating demethylation on core histones and also promoting demethylation of nucleosomal substrates.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation
Article Abstract:
The chromatin remodeling protein Chd1 as a component of SAGA and SLIK is identified. One of the two chromodomains of Chd1 specifically interacts with the methylated lysine 4 mark on histone H3 that is associated with transcriptional activity.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation
Article Abstract:
A study provides the mechanistic insight into the function of arginine methylation at H3R2. It might influence transcription by regulating the H3K4 trimethylation capacity of the Set1 methyltransferase.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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