An expressed pseudogene regulates the messenger-RNA stability of its homologous coding gene
Article Abstract:
The role of an expressed pseudogene in a transgene-insertion mouse mutant exhibiting polycystic kidneys and bone deformity is reported. The findings demonstrated a specific regulatory role of an expressed pseudogene, and pointed to the functional significance of non-coding RNAs.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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Summing up the noise in gene networks
Article Abstract:
The noise associated with the principal steps of the central dogma of molecular biology is examined. The different studies to a simple variant of the fluctuation-dissipation theorem are connected and the experimental controls reinterpret the conclusions.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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