Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels
Article Abstract:
The endocannabinoid anandamide and its metabolite arachidonic acid activating TRPV4 in an indirect way involving the cytochrome P450 epoxygenase-dependent formation of epoxyeicosatrienoic acids are presented. An analysis on this acid identified the endocannabinoids and arachidonic acid as endogenous chemchemical activators of TRP4.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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Enhanced gravi- and phototropism in plant mdr mutants mislocalizing the auxin efflux protein PIN1
Article Abstract:
Research has been conducted on plant mdr mutants. The authors demonstrate that these mutants have faster gravitropism and enhanced phototropism, and that these phenotypes are the results of the disruption of PIN1 protein accumulation along the basal end of hypocotyl cells which are associated with basipetal auxin flow.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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Control of dynamic CFTR selectivity by glutamate and ATP in epithelial cells
Article Abstract:
Research has been copnducted on cystic fibrosis transmembrane conductance regulator. The authors describe the study of phosphorylation- and ATP-independent activation of this regulator by cytoplasmic glutamate.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
User Contributions:
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