Annotation competition spurs Drosophila sequencing efforts
Article Abstract:
Competition between rival bioinformaticists has been used to identify the most accurate computational modelling tools for locating and describing genes hidden within a sequenced genome. An immediate goal was to identify the best tools for annotating the Drosophila genome. The aim is to encourage the bioinformatics community to improve the predictive capabilities of its software tools.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
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Structures by numbers
Article Abstract:
Rapid progress in the fields of genome sequence data and automation mean that structural biology is now becoming structural genomics. This will change how structural biologists work, and how drugs are developed.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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A mutant mouse menagerie
Article Abstract:
Issues are presented concerning the breeding of mice with genetic mutations for use in the study of gene function. The importance of these mice to the understanding of the human genome is discussed.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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- Abstracts: Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy. Eomesodermin is required for mouse trophoblast development and mesoderm formation
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- Abstracts: Inside an intron invasion. Group II intron splicing in vivo by first-step hydrolysis. A tertiary interaction that links active-site domains to the 5' splice site of a group II intron
- Abstracts: Context-dependent nestmate discrimination in the paper wasp, Polistes dominulus: a critical test of the optimal acceptance threshold model