Antibiotics at the crossroads

Article Abstract:

The emerging crisis in wealthy nations and the long-standing crisis in poor nations result from the same causes - economic, regulatory, and scientific - each exacerbated by the problem of antibiotic resistance. All sectors of society, including the pharmaceutical industry, have a major stake in the control of infectious diseases, not only for medical reasons, but also for global economic development and security.

United States, Forecasts, trends, outlooks, Forecasts and trends, Risk factors, Market trend/market analysis, Drug resistance in microorganisms, Microbial drug resistance

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Oxygen and the inflammatory cell

Article Abstract:

Immunologists report the discovery that a single protein causes immune cells to respond to low oxygen levels and switch on the process of inflammation, proving that a relationship exists between hypoxia and inflammation. The article concludes that this research may provide new directions for anti-inflammatory drug development.

Science & research, Causes of, Inflammation, Hypoxia, Anoxia, Proteins, Immunological research, Immunologic research

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Peroxynitrite reductase activity of bacterial peroxiredoxins

Article Abstract:

Research is presented concerning the occurrence of peroxynitrite reductase activity in the genera of bacteria such as Salmonella, Helicobacter and Mycobacterium. The mutagenic, cytotoxic and oxidative properties of peroxynitrite are discussed.

Physiological aspects, Bacteria, Salmonella, Mycobacterium, Helicobacter pylori, Letter to the Editor, Nitrites

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