Average remaining lifetimes can increase as human populations age
Article Abstract:
A new measure of ageing, the median age of the population standardized for expected remaining years of life is proposed. Historical data and forecasts for Germany, Japan, and the United States shows that although these population will be growing older, as measured by their median ages, they will probably experience periods in which they grow younger, as measured by their standardized median ages.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
Article Abstract:
The limited activation of dFOXO reduces expression of the Drosophila insulin-like peptide dilp-2 synthesized in neurons, and represses endogenous insulin-dependent signalling in peripheral fat body. The combination of autonomous and non-autonomous roles of insulin signaling help to control ageing.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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From stem to stern
Article Abstract:
The way in which age-related accumulation of DNA damage and changes in global patterns of gene expression would lead to the decline of stem-cell function is studied in mice. Results reveal that haematopoietic stem cells function is severely impaired in rapidly ageing mutant mice.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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