Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts
Article Abstract:
The apical localization of Inscuteable in Drosophila requires Bazooka, a protein with a PDZ domain. Bazooka localizes with Inscuteable in neuroblasts, binding to the Inscuteable localization domain. Direct biding to Bazooka is thought to mediate the asymmetric localization of Inscuteable.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
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Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon
Article Abstract:
The article describes a biochemical link between the cell cycle and the asymmetric protein localization machinery and indicates that Polo can inhibit progenitor self-renewal by regulation of localization and function of Numb.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl
Article Abstract:
The Drosophila Par protein complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Discusses the research, accompanied by cellular photographs.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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