Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity
Article Abstract:
Hippocampal long-term potentiation and long-term depression are shown to reversibly alter the phosphorylation of AMPA receptors GluR1 subunit.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
User Contributions:
Comment about this article or add new information about this topic:
Phosphorylation and modulation of recombinant GluR6 glutamate receptors by cAMP-dependent protein kinase
Article Abstract:
An experiment using rat GluR6 in a human embryonic kidney provided evidence supporting the position that GluR6 is phosphorylated by cyclic AMP-dependent protein kinase. This shows that glutamate receptor function is modulated at least in part by protein phosphorylation. Therefore, protein phosphorylation is an important mechanism in modulation of ligand-gated ion channels.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
Co-regulation of long-term potentiation and experience-dependent synaptic plasticity in visual cortex by age and experience
Article Abstract:
Long-term potentiation (LTP) is induced in visual cortical slices taken from light-reared and dark-reared rats with varying ages to study LTP's role in the maturation process. The susceptibility to LTP, which is coincidental to the critical period, may be prolonged by raising animals in the dark. Results show that LTP is indicative of a normal mechanism of experience-dependent synaptic modification in the developing brains of mammals.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy. Eomesodermin is required for mouse trophoblast development and mesoderm formation
- Abstracts: Imaging of localized electronic states in the quantum Hall regime. Four-terminal resistance of a ballistic quantum wire
- Abstracts: ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products
- Abstracts: The relative influence of prior residency and dominance on the early feeding behaviour of juvenile Atlantic salmon
- Abstracts: Scavenging by Pheidole pallidula: a key for understanding decision-making systems in ants. How do ants assess food volume?