Connecting with catalysis
Article Abstract:
Combinatorial chemistry has been particularly applied by the pharmaceutical industry over the past 10 years, and it has led to great improvements in the the efficient testing of new molecules for drug activity. The use of similar techniques in other areas including high-speed screening for new solid-state catalysts. Senkan has described such a technique for seeking new heterogeneous catalyst systems, building a 72-site solid-state library of catalyst formulations.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
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Connecting a promotor-bound protein to TBP bypasses the need for a transcriptional activation domain
Article Abstract:
In yeast a promotor-bound protein without an activation domain can induce transcription of DNA if a heterologous DNA-binding domain (LexA) is directly attached to the TATA-binding protein (TBP). The promotor and mutations on the DNA-binding surface influences transcription. In cases, where the protein is bound to the TBP, transcription is induced because the LexA-TBP connection is like the interaction which normally occurs between the activation domain and TBP.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
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Connecting atomistic and mesoscale simulations of crystal plasticity
Article Abstract:
A knowledge of how dislocations leading to crystal plasticity, evolve under stress is necessary to find a quantitative description of plastic deformation in crystalline solids. Molecular-dynamics simulations can elucidate interatomic processes, while dislocation-dynamics simulations examine long-range elastic interactions. The connection between interatomic processes and behaviour on mesoscopic scales was made using large-scale molecular-dynamics simulations.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
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