Crystal structure of the anthrax toxin protective antigen
Article Abstract:
Protective antigen is the most important element of the protein toxin produced by the organism that causes anthrax, Bacillus anthracis. This antigen can transport the toxic enzymes oedema and lethal factors into the cytosol by developing a membrane-inserting heptamer, and can also alter the location of heterologous proteins. The crystal structure of monomeric protective antigen at 2.1 A resolution and the water-soluble heptamer at 4.5 A resolution is discussed.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1997
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Identification of the cellular receptor for anthrax toxin
Article Abstract:
Research is presented concerning the physiological processes which enable the anthrax bacterium to evade the patient's immune system. The cloning of a protective antigen receptor which can protect cells is discussed.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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Crystal structure of the anthrax lethal factor
Article Abstract:
Research is presented concerning the molecular structure of the lethal factor protein which plays an important role in the pathogenesis of anthrax. The four domains which form the crystalline structure are discussed.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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