Crystal structures of fragment D from human fibrogen and its crosslinked counterpart from fibrin
Article Abstract:
A core fragment (fragment D) from human fibrinogen has been found to have an 86K three-chained structure made up of a coiled-coil region and two homologous globular bodies situated around 130 degrees from each other. It was also possible to isolate from human fibrin the covalently bound dimer of fragment D, identified as double-D. This dimer has a structure very similar to that of two molecules of fragment D butted end-to-end, with few conformational changes. The end-to-end association of joined fragments D takes place in a staggered way. This means that a large amount of surface area is occluded between the extremities.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1997
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A period of change
Article Abstract:
The discovery of the first accreting millisecond X-ray pulsar is reported by Wijnands and van der Klis, and Chakrabarty and Morgan, bridging an important gap in the theory of how pulsars evolve. Observations have been made by the Rossi X-ray Timing Explorer (RXTE) and the new x-ray pulsar provides proof that millisecond radio pulsars are born in x-ray binaries. A millisecond x-ray pulsar needs a neutron star with a much weaker magnetic field, so that the size of the magnetosphere corresponds to the orbital period of a millisecond.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
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