Distinguishable functions for engrailed and invected in anterior-posterior patterning in the Drosophila wing
Article Abstract:
Anterior-posterior patterning in the Drosophila wing requires the overlapping functions of invected (inv) and engrailed (en) homeobox genes. Incomplete morphological transformation from posterior to anterior fate in the wing occurs in the absence of en with an ectopic anterior-posterior organizer is not produced. However, only when both en and inv are removed does complete transformation occur. This research supports the involvement of inv in regulating the specific target genes for posterior fate specification but not in the expression of effector genes.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
User Contributions:
Comment about this article or add new information about this topic:
Modulation of enhancer-promoter interactions by insulators in the Drosophila embryo
Article Abstract:
Insulator DNAs in the Drosophila embryo act only locally to block the interactions between enhancers and promoters rather than causing permanent chromatin structure changes while the blocking appears specifically targeted. These functions provide evidence that the insulators serve a broader function than just isolating the interactions by also modulating and regulating the promoter-enhancer interactions within complex promoters and complex genetic loci.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
User Contributions:
Comment about this article or add new information about this topic:
Evolutionary origin of insect wings from ancestral gills
Article Abstract:
There are two theories on the origin of insect wings. The first theory proposes that wings evolved by modification of limb branches present in multibranched ancestral appendages and functioned as gills. The other theory holds that wings evolved as novel outgrowths of the body wall, not directly related to any pre-existing limbs. A study based on gene expression patterns has provided support for the first theory.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1997
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Direct integration of Hox and segmentation gene inputs during Drosophila development
- Abstracts: Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
- Abstracts: Conscious and unconscious emotional learning in the human amygdala. Staring fear in the face
- Abstracts: Missing lithotroph identified as new planctomycete. Hyperion the sponge. The urban organism
- Abstracts: Another important organ. A functional circuit underlying male sexual behavior in the female mouse brain. Females can also be from Mars