Effect of dietary cysteine supplements on canola meal toxicity and altered hepatic glutathione metabolism in the rat
Article Abstract:
Evidence for toxicity of canola meal was seen in reduced growth rates and general hepatotoxicity, observed as liver enlargement. Glutathione transport from the liver to the periphery may be impaired, resulting in reduced detoxification and increased cellular damage. The hepatic glutathione detoxification system in rats was found to be altered, with increased levels of glutathione and increased activity of glutathione-S-transferase (GSH-S-T). Supplemental cysteine reduced GSH-S-T activity in canola-fed rats, indicating a possible protective effect.
Publication Name: Journal of Animal Science
Subject: Zoology and wildlife conservation
ISSN: 0021-8812
Year: 1992
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Effects of hydrated sodium calcium aluminosilicate on fescue toxicosis and mineral absorption
Article Abstract:
A study was conducted to evaluate the potential of hydrated sodium calcium aluminosilicate (HSCAS), in protecting livestock from fescue toxicosis. Additionally, the effect of HSCAS on mineral absorption was studied. Rats in the experimental group were fed with endophyte-infested tall fescue seeds while those in the control group were fed with uninfested seeds. HSCAS was not found to have any significant protective action against fescue toxicosis and HSCAS intake decreased absorption of minerals such as magnesium, zinc and manganese.
Publication Name: Journal of Animal Science
Subject: Zoology and wildlife conservation
ISSN: 0021-8812
Year: 1992
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