Ephrin signalling controls brain size regulating apoptosis of neural progenitors
Article Abstract:
The ephrin-A/EphA receptor signalling plays a key role in controlling the size of the mouse cerebral cortex by regulating cortical progenitor cell apoptosis. The results indicate that ephrin/Eph signalling is identified as a physiological trigger for apoptosis that can alter brain size and shape by regulating the number of neural progenitors.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Divide and conquer
Article Abstract:
The mitochondria in mammalian cells fragment into smaller pieces when the cells die by the process of apoptosis. It is concluded that the release of mitochondrial proteins stimulates mitochondrial division and it is indicated that mitochondrial fragmentation is caspase-independent which means that is an early event in the apoptotic programme.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Suppression of CED-3-independent apoptosis by mitochondrial beta NAC in Caenorhabditis elegans
Article Abstract:
Caenorhabditis elegans inhibitor of cell death-1 (ICD-1) is necessary and sufficient to prevent apoptosis. Cells must integrate developmental information with regulatory inputs to control the switch between repressing and activating apoptosis.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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