Biochemist strikes gold

Article Abstract:

An estimated $3-million-plus deal was signed with Merck, aimed at developing drugs to battle a leading cause of blindness by Harvard University and one of its biological chemists, Robert Rando. The agreement allows the New Jersey drug company to obtain exclusive licenses to a family of candidate small-molecule drugs that Rando, a specialist in the biology of vision, has discovered and patented hoping to find a drug that slows or prevents age-related macular degeneration, a disease of the retina.

United States, Product development, Research and Development in the Physical, Engineering, and Life Sciences, Contracts & orders received, Pharmaceutical preparations, Alliances, partnerships, Licensing/Sales Agreements, Contracts & orders let, Chemists, Pharmaceutical industry, Contracts, Licensing agreements, Company licensing agreement, Contract agreement, Harvard University, Merck & Company Inc., Ophthalmic solutions, Rando, Robert

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Centocor staggered by poor clinical results

Article Abstract:

Biotechnology company Centocor Inc stopped clinical testing of its product, Centoxin or HA-1A, after the deaths of several Gram-negative bacteremia patients who had received the new drug. Centoxin is a human monoclonal antibody that Centocor developed for treatment of Gram-negative sepsis and septic shock. The disastrous test results make it unlikely that Centoxin will ever be used and also caused Centocor's stock to drop 62% in price.

Biological products exc. diagnostic, Diagnostic substances, Biotechnology industry, Biotechnology industries, Product information, Complications and side effects, Drug therapy, Septic shock, Gram-negative bacterial infections, Centocor Inc., Centoxin (Medication)

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