Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
Article Abstract:
Familial amyotrophic lateral sclerosis (FALS) may result from mutations of the gene that encodes a cytosolic, copper/zinc-binding superoxide dismutase, which is also a metalloenzyme that inhibits the toxic effect of superoxide anions or free oxygen radicals. FALS is the inherited form of ALS, in which motor neurons in the cortex, brainstem and spinal cord degenerate. The association of FALS with free oxygen radicals may lead to new treatments that target the radicals.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
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MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
Article Abstract:
The molecular characterization of the gene MOD-1 demonstrates the existence of a 5-HT-gated chloride channel that modulates locomotory behaviour in the nematode Caenorhabditis elegans.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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Phagocytosis promotes programmed cell death in C. elegans
Article Abstract:
Research describing programmed cell death in the nematode Caenorhabditis elegans is presented. In particular the role of engulfment genes is investigated.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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