New wrinkles in cytokinesis
Article Abstract:
Burton and Taylor have devised a simple and elegant method for directly observing the weak traction forces that emerge during the cytokinesis process. Their method involves the examination of deformation of rubber sheets, or wrinkles, which can be used to measure the amount and direction of the force produced by the moving cells. The study indicates that the cell's progression through mitosis is accompanied by the growth in the traction at the cell equator.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1997
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Regulation of cell movement is mediated by stretch-activated calcium channels
Article Abstract:
Intracellular calcium controls many molecular process required for cell movement. It is not known how calcium controls overall cell movement. Transient increases in intracellular calcium during the locomotion of fish epithelial keratocytes were found to happen more frequently in cells that are temporarily stuck to the substratum or when mechanically stretched. Calcium transients occur from the activation of stretch-activated calcium channels.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
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Principles of locomotion for simple-shaped cells
Article Abstract:
A kinematic description of locomotion of fish epidermal keratocytes is presented. These cells exhibit semicircular shape and persistent 'gliding' motion. It is proposed that the extension on the front and retraction of the rear of these cells occurs orthogonal to the cell edge. In addition, a graded distribution of extension and retraction rates along the cell margin maintains cell shape and size during locomotion.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
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