Origins of Old Testament priests
Article Abstract:
It is shown that Levite Y chromosomes are diverse, but Cohen chromosomes are homogeneous. The origin of the Cohen chromosomes has been traced to around 3,000 years before present, early in the Temple period. Y-chromosome-specific variation was characterized at six microsatellites and six unique event polymorphisms (UEPs) in 306 male Jews. A modal cluster of related chromosomes was defined as the modal haplotype. With the relative isolation of Ashkenazic and Sephardic communities, the presence of the same modal haplotype in the Cohanim of each community indicates a common origin.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
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Understanding human diversity
Article Abstract:
Modern genetics are successful at tracking down the genetic abnormalities that lead to diseases that are inherited in a simple way in families, such as cystic fibrosis or Tay-Sachs disease and the genetic disorders to which many would yield are more complex ones such as cancer, or cardiovascular and neurodegenerative diseases. Regarding this, the principal goal of the HapMap Consortium is to discover the associations among variants and the first phase of project consists of compiling data on the genotypes.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
Article Abstract:
The genome-wide association (GWA) studies for approximately 14,000 cases of seven common diseases and 3,000 shared controls are presented. The studies present a powerful approach for the identification of genes involved in common human diseases, hence being extremely beneficial for human genetics research.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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