Proteins downhill all the way
Article Abstract:
Nuclear magnetic resonance (NMR) spectroscopy is used to follow the unfolding of an all-helical protein known as BBL, to verify whether proteins are either completely folded or completely unfolded. Observations reveal that BBL folds in a 'downhill' fashion, that is, the process is characterized by very low energy barriers between the folded and unfolded states, and when downhill folders are subject to conditions like heat stress, they are predicted to unfold gradually.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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Shifting light with spin
Article Abstract:
A radically different method to detect nuclear magnetic resonance (NMR) in liquids, called the nuclear-spin optical rotation (NSOR), is proposed by which small phase-shifts induced in a laser beam by nuclear spins are observed as the beam passes through a liquid. NSOR can work with very small, tightly focused laser beams, and is enhanced by hyperfine effects that increase the mass of the nucleus, making the technique particularly suitable for heavy nuclei.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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NMR on chip
Article Abstract:
Nuclear magnetic resonance (NMR) spectroscopy, a near-ubiquitous technique in the physical and biological sciences, that is used to verify molecular structures in synthetic chemistry, investigation of superconductivity in solid-state physics is studied. A device for quantum computing using metal coils is presented.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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