Rapid communication: a restriction fragment length polymorphism in the porcine leptin receptor (LEPR) gene
Article Abstract:
PCR amplification of the porcine leptin receptor gene resulted in the identification of a HinfI PCR-RFLP polymorphism. This polymorphism exhibited a Mendelian inheritance pattern in six three-generation families of the swine involved in the study. LEPR is a high-affinity receptor for the hormone leptin which was found to be responsible for regulating fat deposition and satiety. Mutation of this gene has been associated with mice and rat obesity.
Publication Name: Journal of Animal Science
Subject: Zoology and wildlife conservation
ISSN: 0021-8812
Year: 1997
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Rapid communication: genetic linkage and physical mapping of the porcine androgen receptor (AR) gene
Article Abstract:
A study was conducted to analyze the genetic linkage and physical mapping of the androgen receptor gene in pigs. To this end, primers were designed from published bovine and human androgen receptor sequences. Polymerase chain reaction carried out utilizing primers AR-3 and AR-4. The AR gene supports eight exons and a total genomic size of about 90 kb in humans. Findings indicated a microsatellite similar in the bovine AR gene.
Publication Name: Journal of Animal Science
Subject: Zoology and wildlife conservation
ISSN: 0021-8812
Year: 1999
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Rapid communication: a novel DNA polymorphism of the porcine myogenin (MYOG) gene
Article Abstract:
A 1,644-bp fragment of the porcine myogenin (MYOG) gene was amplified from the porcine genomic DNA via polymerase chain reaction (PCR) techniques involving the NlaIV. The purified PCR product was composed of two polymorphic 520- and 480-bp fragments and one monomorphic 360-bp fragment. The porcine MYOG was also characterized as a MyoD skeletal muscle transcription factor that was localized in the porcine chromosome nine.
Publication Name: Journal of Animal Science
Subject: Zoology and wildlife conservation
ISSN: 0021-8812
Year: 1997
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