Reversal in the direction of movement of a molecular motor
Article Abstract:
Kinesin and non-claret disjunctional (ncd) molecular motors move in opposite directions through microtubules. The basis for the direction of movement is not clear, but could be an intrinsic property of the motor domain. A chimaera made up of the motor domain of the minus-end-directed kinesin of Neurospora crassa, was found to move towards the plus end of the microtubules. This shows a reversal of the polarity of force geneation of the ncd motor domain.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1997
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Switching on kinesin
Article Abstract:
The crystallization in a motor region of the enzyme kinesin in two different functional states, helped researchers to understand how kinesin works. A 20 degree twist of kinesin's motor region lets the enzyme grip more tightly onto the linear tracks, called microtubules, as it moves along.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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A step dissected
Article Abstract:
The results from single-molecule fluorescence technique that provide insight into walking mechanism of molecular motor protein kinesin through hydrolysis of ATP molecule are reported.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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