Signalling through the lipid products of phosphoinositide-3-OH kinase
Article Abstract:
It is known that stimulatory agonist molecules binding at the exterior of cell membranes cause a lipid second messenger to send the signal to the cell's interior. The actions of enzymes phosphoinositide-3-OH kinase (Pl(3)K) or phospholipase can extract such second messengers from phospholipids in the membrane. Pl(3)K is a crucial component of many cellular responses, such as shape alteration and the movement of organelle membranes. The role of Pl(3)K in the mediation of cellular responses is discussed.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1997
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Picture perfect: medical imaging techniques are being adapted to study gene expression and other cellular activities in living animals
Article Abstract:
It is becoming increasingly common for top cell biologists, geneticists and molecular biologists to work with experts in magnetic resonance imaging, optical imaging and positron emission tomography. It has been possible to develop chemical probes to make molecular targets 'light up' in magnetic resonance imaging, positron emission tomography or other optical images.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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