Targeted gene knockdown experiments: Combining (super 18)O-Isotopic labeling and protein-AQUA(super TM)
Article Abstract:
(super 18)O enzymatic labeling and protein-AQUA is used in combination to provide a synergistic and efficient approach for the analysis of gene knockdown experiments. Protein-AQUA analysis enable absolute quantitation of the protein targeted for gene knockdown as the O enzymatic method is a global labeling procedure, and it allows for the elucidation of off-target effects, as well as the identification of related protein products affected by the knockdown event.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Written in blood
Article Abstract:
The potential use of carrier-protein-bound low-molecular-weight (LMW) blood biomarkers in blood proteomics is depicted. The combination of artificial intelligence, clinical proteomics and nanotechnology to monitor blood- biomarker archive will revolutionizing disease diagnosis carrier-protein-bound low-molecular-weight and health profile.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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An attractive force in metastasis
Article Abstract:
Issues are presented concerning the influence of metastasis in the failure of the treatment of patients suffering from cancer. The role played by soluble factors in attracting circulating cancer cells is discussed.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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